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02Flagship caseExploring

Clinical Workflow

Stage-bound execution with independent validation and human review.

A staged clinical statistics workflow connecting approved inputs, repeatable execution, independent validation, and professional review.

Project roles

Product Owner · Statistician · Systems Architect · Primary Builder

01 / The work problem

Specifications, programs, outputs, validation, and review can drift into separate tools and informal hand-offs, making state and accountability difficult to reconstruct.

02 / Workflow change

Each clinical stage begins with approved inputs and a defined scope, then moves through execution, independent validation, professional review, and a documented hand-off to the next stage.

03 / From input to review

Inputs, execution, validation, and review remain traceable.

  1. 01

    Identify the working stage from the current Study state

  2. 02

    Assemble the approved specification and relevant context

  3. 03

    Run repeatable tasks and organize the stage results

  4. 04

    Check source relationships, result structure, and execution records

  5. 05

    Complete professional review and confirm the stage deliverable

04A / Professional judgment

Statisticians and reviewers own stage decisions, specifications, exception handling, scientific interpretation, and result approval.

04B / System support

The system turns approved specifications into repeatable tasks, organizes results and consistency checks, prepares review materials, and records relationships between stages.

05 / Verified evidence

Current capabilities verified against project sources.

  1. 01

    The current foundation defines ten clinical statistics stages spanning Protocol, SAP, SDTM, ADaM, TFL, QC, and Submission, with action selection, review records, and knowledge-version references.

    Source · clinical-workflow · PROJECT_SPEC.md
  2. 02

    The stages follow clinical-statistics business dependencies, with connected inputs, results, and review status.

    Source · clinical-workflow · PROJECT_GUIDE.md
  3. 03

    Specifications, execution, result checks, and run records now share one traceable flow that is being exercised through representative clinical deliverables.

    Source · clinical-workflow · PROJECT_SPEC.md
  4. 04

    Professional review decisions are retained with their context, processing record, and project state.

    Source · clinical-workflow · PROJECT_SPEC.md

06 / Project status

Implemented capabilities and planned extensions.

Current

  • Fixed clinical stages, action selection, structured review, knowledge-version references, and representative deliverable flows

Exploring

  • Continuous run records, stage specifications, repeatable execution, independent validation, and stage-delivery management

Long-term

  • A complete Study workflow connecting reviewed knowledge, statistical decisions, program execution, and quality review

07 / Workflow foundation

  • Clinical stages and business dependencies
  • Versioned specifications and run records
  • Independent validation and professional review
  • Traceable stage delivery

Workflow context

View complete workflow →

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